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Giorgia Imparato Write a Message

Technologist

Center

CABHC@CRIB Napoli

Contacts

Largo Barsanti e Matteucci
+39 081 19933126 / +39 081 19933128

About

Dr. Giorgia Imparato received her Masters Science in Materials Engineering from the University of Naples "Federico II" in Jenuary 2003, discussing an experimental thesis on optimization of process conditions to engineer cartilage tissue equivalent in vitro. From 2003 to 2004 she has a fellowship funded by FP6 the EU’s framework programme “Dermagenesis: bio-engineering of leather: structure design, biosynthesis – Towards zero emission production” COLL-CT-2003-500224-2 working at the Interdisciplinary Research Centre of Biomaterials (CRIB). From 2005 to 2008 she worked as PhD student at the Department of Materials and Production Engineering of the University of Naples "Federico II". For her doctoral studies she was mainly interested in processing of tissue biohybrid in vitro. In particular, she focused her attention on the design of a novel strategy to build up 3D tissue equivalent in vitro. In February 2009 she received her PhD in Materials and Structures Engineering from the University of Naples "Federico II". From May 2009 to May 2011 she worked at the Interdisciplinary Research Centre of Biomaterials (CRIB) of Naples for the realization, processing and characterization of tissue enquivalent in vitro, in particular connective equivalent tissues. At the present, she is a senior post-doc researcher at the Center for Advanced Biomaterials for health Care (CABHC) - Istituto Italiano di Tecnologia of Naples and her research deals with the realization of complex 3D tissue equivalent in vitro.

 

Projects

She is PI in the project "Interconnecting artificial and living systems for advanced prosthetics"

selected as winning project for the Interdepartmental/Interdisciplinary Projects, launched in May 2012.

Selected Publications

Time and space evolution of transport properties in agarose-chondrocyte constructs

ED Rosa, F Urciuolo, C Borselli, D Gerbasio, G Imparato, PA Netti
Tissue engineering 12 (8), 2193-2201 2006

Strategia bottom up per la produzione di bioibridi tessutali in vitro
G Imparato
Facoltà di Ingegneria Università di Napoli Federico II 2008

Effect of dynamic loading on solute transport in soft gels implication for drug delivery
F Urciuolo, G Imparato, PA Netti
AIChE Journal 54 (3), 824-834 2008

Engineered dermal equivalent tissue in vitro by assembly of microtissue precursors
C Palmiero, G Imparato, F Urciuolo, P Netti
Acta Biomaterialia 6 (7), 2548-2553 2010

Complementary therapeutic effects of dual delivery of insulin-like growth factor-1 and vascular endothelial growth factor by gelatin microspheres in experimental heart failure
A Cittadini, MG Monti, V Petrillo, G Esposito, G Imparato, A Luciani, F ...
European journal of heart failure 13 (12), 1264-1274 2011

IN VITRO BIOENGINEERED ANIMAL TISSUE FIBER AND ITS USE IN THE TEXTILE INDUSTRY
P NETTI, G IMPARATO, F URCIUOLO
WO Patent WO/2011/051,983 2011

Effect of Process Conditions on the Growth of Three-Dimensional Dermal-Equivalent Tissue Obtained by Microtissue Precursor Assembly
F Urciuolo, G Imparato, C Palmiero, A Trilli, PA Netti
Tissue Engineering Part C: Methods 17 (2), 155-164 2011

Novel strategies to engineering biological tissue in vitro.
F Urciuolo, G Imparato, A Guaccio, B Mele, PA Netti
Methods in molecular biology (Clifton, NJ) 811, 223 2012

The role of microscaffold properties in controlling the collagen assembly in 3D dermis equivalent using modular tissue engineering
G Imparato, F Urciuolo, C Casale, PA Netti
Biomaterials Volume 34, Issue 32, October 2013, Pages 7851–7861

Building a tissue in vitro from the bottom up: implications in regenerative medicine.Urciuolo F, Imparato G, Totaro A, Netti PA. Methodist Debakey Cardiovasc J. 2013 Oct;9(4):213-217

Fabrication of 3D tissue equivalent: an in vitro platform for understanding collagen evolution in healthy and diseased models. F. Urciuolo, G. Imparato, C. Casale, S. Scamardella, P. Netti Proc. of SPIE Vol. 8792 87920K!1; May 2013

Building a Tissue In Vitro from the Bottom Up: Implications in Regenerative Medicine. Francesco Urciuolo, Ph.D.; Giorgia Imparato, Ph.D.; Alessandra Totaro, Ph.D.; Paolo A. Netti, Ph.D. Oct 2013 " Methodist DeBakey cardiovascular journal

PCL–HA microscaffolds for in vitro modular bone tissue engineering. A. Totaro !A. Salerno " G. Imparato " C. Domingo " F, Urciuolo " P. A. Netti. Journal of Tissue Engineering and Regenerative Medicine. 7 SEP 2015

Method for producing a totally endogenous bioengineered tissue and tissue obtained thereby WO 2015166455 A1. PCT/IB2015/053166 5 nov 2015

Biophysical properties of dermal building-blocks affect extra cellular matrix assembly in 3D endogenous macrotissue. F. Urciuolo, A. Garziano, G. Imparato, V. Panzetta, S. Fusco, C. Casale, P A Netti. Biofabrication 8. January 2016

A micro-perfusion bioreactor for on line investigation of ECM remodeling under hydrodynamic and biochemical stimulation. A. Garziano, F. Urciuolo, G. Imparato, F. Martorina, B. Corrado P A Netti. Lab on chip Feb 2016.

A novel engineered dermis for in vitro photodamage research. G. Imparato, C. Casale, S. Scamardella, F. Urciuolo, M. Bimonte, F. Apone, G. Colucci and PA Netti. J Tissue Eng Regen Med (2016). DOI: 10.1002/term.2125

Endogenous human skin equivalent promotes in vitro morphogenesis of follicle-like structures

C Casale, G Imparato, F Urciuolo, PA Netti

Biomaterials 101, 86-95

3D is not enough: Building up a cell instructive microenvironment for tumoral stroma microtissues

V Brancato, A Garziano, F Gioiella, F Urciuolo, G Imparato, V Panzetta, ...

Acta Biomaterialia

Engineered cardiac micromodules for the in vitro fabrication of 3D endogenous macro-tissues

A Totaro, F Urciuolo, G Imparato, PA Netti

Biofabrication 8 (2), 025014

 

 

 

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I numeri di IIT

L’Istituto Italiano di Tecnologia (IIT) è una fondazione di diritto privato - cfr. determinazione Corte dei Conti 23/2015 “IIT è una fondazione da inquadrare fra gli organismi di diritto pubblico con la scelta di un modello di organizzazione di diritto privato per rispondere all’esigenza di assicurare procedure più snelle nella selezione non solo nell’ambito nazionale dei collaboratori, scienziati e ricercatori ”.

IIT è sotto la vigilanza del Ministero dell'Istruzione, dell'Università e della Ricerca e del Ministero dell'Economia e delle Finanze ed è stato istituito con la Legge 326/2003. La Fondazione ha l'obiettivo di promuovere l'eccellenza nella ricerca di base e in quella applicata e di favorire lo sviluppo del sistema economico nazionale. La costruzione dei laboratori iniziata nel 2006 si è conclusa nel 2009.

Lo staff complessivo di IIT conta circa 1440 persone. L’area scientifica è rappresentata da circa l’85% del personale. Il 45% dei ricercatori proviene dall’estero: di questi, il 29% è costituito da stranieri provenienti da oltre 50 Paesi e il 16% da italiani rientrati. Oggi il personale scientifico è composto da circa 60 principal investigators, circa 110 ricercatori e tecnologi di staff, circa 350 post doc, circa 500 studenti di dottorato e borsisti, circa 130 tecnici. Oltre 330 posti su 1400 creati su fondi esterni. Età media 34 anni. 41% donne / 59 % uomini.

Nel 2015 IIT ha ricevuto finanziamenti pubblici per circa 96 milioni di euro (80% del budget), conseguendo fondi esterni per 22 milioni di euro (20% budget) provenienti da 18 progetti europei17 finanziamenti da istituzioni nazionali e internazionali, circa 60 progetti industriali

La produzione di IIT ad oggi vanta circa 6990 pubblicazioni, oltre 130 finanziamenti Europei e 11 ERC, più di 350 domande di brevetto attive, oltre 12 start up costituite e altrettante in fase di lancio. Dal 2009 l’attività scientifica è stata ulteriormente rafforzata con la creazione di dieci centri di ricerca nel territorio nazionale (a Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) e internazionale (MIT ed Harvard negli USA) che, unitamente al Laboratorio Centrale di Genova, sviluppano i programmi di ricerca del piano scientifico 2015-2017.

IIT: the numbers

Istituto Italiano di Tecnologia (IIT) is a public research institute that adopts the organizational model of a private law foundation. IIT is overseen by Ministero dell'Istruzione, dell'Università e della Ricerca and Ministero dell'Economia e delle Finanze (the Italian Ministries of Education, Economy and Finance).  The Institute was set up according to Italian law 326/2003 with the objective of promoting excellence in basic and applied research andfostering Italy’s economic development. Construction of the Laboratories started in 2006 and finished in 2009.

IIT has an overall staff of about 1,440 people. The scientific staff covers about 85% of the total. Out of 45% of researchers coming from abroad 29% are foreigners coming from more than 50 countries and 16% are returned Italians. The scientific staff currently consists of approximately 60 Principal Investigators110 researchers and technologists350 post-docs and 500 PhD students and grant holders and 130 technicians. External funding has allowed the creation of more than 330 positions . The average age is 34 and the gender balance proportion  is 41% female against 59% male.

In 2015 IIT received 96 million euros in public funding (accounting for 80% of its budget) and obtained 22 million euros in external funding (accounting for 20% of its budget). External funding comes from 18 European Projects, other 17 national and international competitive projects and approximately 60 industrial projects.

So far IIT accounts for: about 6990 publications, more than 130 European grants and 11 ERC grants, more than 350 patents or patent applications12 up start-ups and as many  which are about to be launched. The Institute’s scientific activity has been further strengthened since 2009 with the establishment of 11 research nodes throughout Italy (Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) and abroad (MIT and Harvard University, USA), which, along with the Genoa-based Central Lab, implement the research programs included in the 2015-2017 Strategic Plan.