We are seeking a fellow candidate to join the Cancer Biology team led by Dr. Stefano Campaner within the Genomic Science Research Line at the Center for Genomic Science of Istituto Italiano di Tecnologia (IIT) in Milan, Italy (https://cgs.iit.it/research/cancer-biology), coordinator Dr. Francesco Nicassio.
The Center for Genomic Science of IIT@SEMM (http://genomics.iit.it ) benefits from state-of-the-art facilities and advanced technologies. The successful candidate will be integrated in a lively community of experimental and computational scientists.
Our group has a long-standing interest in understanding the molecular mechanisms of transformation induced by oncogenic transcription factors such as Myc and the Hippo pathway co-activators YAP and TAZ.
The selected candidate will work on the characterization of a number of novel YAP/TAZ regulators that we recently identified by a loss of function genetic screen (unpublished), with the aim of addressing their relevance in cancer stem cells regulation, chemoresistance and metastasis in Breast and Liver Cancer models. Emphasis will be placed in (i) understanding upstream regulatory mechanisms (ii) the dissection of transcriptional and epigenetic networks (RNA-seq, ChIP-seq, single-cells RNA-seq), both in-vitro and in-vivo and (iii) in-vivo genetic studies based on orthotopic models.
The ideal candidate should be trained in basic molecular biology techniques, cell culture and basic biochemistry. Previous experience in working with in-vivo models, organoids or in Next Generation Sequencing techniques will be highly valued.
The candidate will work in the framework of the project “Functional and phenotypic characterization of novel TAZ regulators” supported by AIRC IG Grant 2018 (project code 21663).
Required skills and experience
Applications should be e-mailed to both email@example.com and firstname.lastname@example.org and include a CV, a short statement about professional skills and interests and name and contacts of two referees.
Candidates should also ask to one of the referees mentioned in the application to send a reference letter directly to email@example.com and firstname.lastname@example.org. Selected candidates will be initially interviewed by Skype.
Application deadline: June 30, 2019 or until the position is filled.
Fondazione Istituto Italiano di Tecnologia – IIT (www.iit.it) - was founded with the objective of promoting Italy’s technological development and further education in science and technology. In this sense IIT is committed to achieving its scientific program, which sees a major inspirational principle in the integration between basic scientific research and the development of technical applications. Research at IIT cover scientific areas of high innovative content, representing the most advanced frontiers of modern technology, with wide application possibilities in various fields from medicine to industry, from computer science to robotics, life sciences and nanobiotechnology.
Istituto Italiano di Tecnologia is an Equal Opportunity Employer that actively seeks diversity in the workforce.
Please note that the data that you provide will be used exclusively for the purpose of professional profiles’ evaluation and selection, and in order to meet the requirements of Istituto Italiano di Tecnologia.
Your data will be processed by Istituto Italiano di Tecnologia, based in Genoa, Via Morego 30, acting as Data Controller, in compliance with the rules on protection of personal data, including those related to data security.
Please also note that, pursuant to articles 15 et. seq. of European Regulation no. 679/2016 (General Data Protection Regulation), you may exercise your rights at any time by contacting the Data Protection Officer (phone +39 010 28961 - email: dpo[at]iit.it)