Postdoctoral Fellowship in MR-Guided Hyperthermia - [ Postdoc ]

Workplace: Genova, IIT
Added on: 29/06/2018 - Expires on: 15/08/2018

The Nanotechnology for Precision Medicine Research Line at IIT invites a sharp, enthusiastic, well-trained candidate to work on the development of MR-guided hyperthermia using focused radio frequency. This project involves the development of a new therapeutic modality for neurological and neurodevelopmental disorders, based on novel concepts in focused RF. The goal is to develop algorithms and hardware aiming to non-invasively generate controlled local SAR hotspots and hyperthermia to modulate the permeability of the blood-brain barrier to molecules, nanoparticles and cells.

The ideal candidate will be supported for at least 2 years and will work at the interface of two laboratories: the Decuzzi Lab at the Istituto Italiano di Tecnologia and the Rutt Lab at the Lucas Center for Imaging (Stanford, CA). Decuzzi lab focuses on the design, production and development of nanoparticles for drug delivery and multimodal imaging in a variety of diseases, including cancer, cardiovascular and brain-related disorders. Rutt lab focuses on ultra-high field (7T and above) MRI technology development and applications. Ongoing applications projects include UHF MRI studies of multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, essential tremor, and traumatic brain injury.

Experience and Skills

Minimum:

  • PhD in engineering, physics, biomedical engineering, biophysics, or related discipline
  • Experience with numerical modeling packages such as Sim4Life, CST, FEKO, HFSS, COMSOL
  • Experience with RF coil design and construction: transmit/receive coils, receive arrays, transmit arrays
  • Programming experience (Matlab, other scientific and software development environments)

Desirable:

  • Experience with circuit modeling software like ADS or AWR
  • Experience with CAD modeling using Autocad, Solidworks or similar packages
  • Basic electronics and mechanical workshop experience (e.g. on a CNC mill)

Available Facilities

The Decuzzi and Rutt Labs include the following facilities and key equipment:

Electronics shop: Keysight E5080A VNA, 4 ports; Keysight FieldFox VNA, 2 Ports; Anritsu VNA, 1 port; Keysight DSO 7054B Oscilloscope; Tektronix DPO 4054 Oscilloscope; SPEAG DAK 12 probe

Machine shop: Tormach 770 CNC Mill; Stratasys Fortus 360mc 3D printer

MR scanners: one 7T GE Discovery MR950 (with 8ch pTx), one 3T GE Discovery MR750, one 3T GE Signa Premier, and one 3T GE Signa PET-MR (all 100% available for research, software compatibility between all scanners), as well as multiple animal MR scanners ranging from 3T to 11.7T.

Nanomedicine laboratory: DLS, Multisizer, TEM, SEM, ICP-MS, Clean Room facility with EBL and DLW for nano/microfabrication.

Please apply by August 15, 2018. Please submit your application, including a detailed CV, statement of research experience and interests, and contact information of two referees to: Paolo Decuzzi, ( This email address is being protected from spambots. You need JavaScript enabled to view it. ) quoting: “Postdoctoral Fellowship in MR-Guided Hyperthermia CB 74292”.

 

We inform you that the information you provide will be used solely for the purposes of evaluating and selecting professional profiles in order to meet the requirements of Istituto Italiano di Tecnologia.

Your data will be processed by Istituto Italiano di Tecnologia, based in Genoa, Via Morego 30, acting as Data Controller, in compliance with the rules on protection of personal data, including those related to data security.

Please also note that, pursuant to articles 15 et. seq. of European Regulation no. 679/2016 (General Data Protection Regulation), you may exercise your rights at any time by contacting the Data Protection Officer (phone +39 010 71781 - email: This email address is being protected from spambots. You need JavaScript enabled to view it.).

Istituto Italiano di Tecnologia is an Equal Opportunity Employer that actively seeks diversity in the workforce.

Contacts
Paolo Decuzzi
This email address is being protected from spambots. You need JavaScript enabled to view it.
Involved Research lines
Nanotechnology for Precision Medicine

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I numeri di IIT

L’Istituto Italiano di Tecnologia (IIT) è una fondazione di diritto privato - cfr. determinazione Corte dei Conti 23/2015 “IIT è una fondazione da inquadrare fra gli organismi di diritto pubblico con la scelta di un modello di organizzazione di diritto privato per rispondere all’esigenza di assicurare procedure più snelle nella selezione non solo nell’ambito nazionale dei collaboratori, scienziati e ricercatori ”.

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Lo staff complessivo di IIT conta circa 1440 persone. L’area scientifica è rappresentata da circa l’85% del personale. Il 45% dei ricercatori proviene dall’estero: di questi, il 29% è costituito da stranieri provenienti da oltre 50 Paesi e il 16% da italiani rientrati. Oggi il personale scientifico è composto da circa 60 principal investigators, circa 110 ricercatori e tecnologi di staff, circa 350 post doc, circa 500 studenti di dottorato e borsisti, circa 130 tecnici. Oltre 330 posti su 1400 creati su fondi esterni. Età media 34 anni. 41% donne / 59 % uomini.

Nel 2015 IIT ha ricevuto finanziamenti pubblici per circa 96 milioni di euro (80% del budget), conseguendo fondi esterni per 22 milioni di euro (20% budget) provenienti da 18 progetti europei17 finanziamenti da istituzioni nazionali e internazionali, circa 60 progetti industriali

La produzione di IIT ad oggi vanta circa 6990 pubblicazioni, oltre 130 finanziamenti Europei e 11 ERC, più di 350 domande di brevetto attive, oltre 12 start up costituite e altrettante in fase di lancio. Dal 2009 l’attività scientifica è stata ulteriormente rafforzata con la creazione di dieci centri di ricerca nel territorio nazionale (a Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) e internazionale (MIT ed Harvard negli USA) che, unitamente al Laboratorio Centrale di Genova, sviluppano i programmi di ricerca del piano scientifico 2015-2017.

IIT: the numbers

Istituto Italiano di Tecnologia (IIT) is a public research institute that adopts the organizational model of a private law foundation. IIT is overseen by Ministero dell'Istruzione, dell'Università e della Ricerca and Ministero dell'Economia e delle Finanze (the Italian Ministries of Education, Economy and Finance).  The Institute was set up according to Italian law 326/2003 with the objective of promoting excellence in basic and applied research andfostering Italy’s economic development. Construction of the Laboratories started in 2006 and finished in 2009.

IIT has an overall staff of about 1,440 people. The scientific staff covers about 85% of the total. Out of 45% of researchers coming from abroad 29% are foreigners coming from more than 50 countries and 16% are returned Italians. The scientific staff currently consists of approximately 60 Principal Investigators110 researchers and technologists350 post-docs and 500 PhD students and grant holders and 130 technicians. External funding has allowed the creation of more than 330 positions . The average age is 34 and the gender balance proportion  is 41% female against 59% male.

In 2015 IIT received 96 million euros in public funding (accounting for 80% of its budget) and obtained 22 million euros in external funding (accounting for 20% of its budget). External funding comes from 18 European Projects, other 17 national and international competitive projects and approximately 60 industrial projects.

So far IIT accounts for: about 6990 publications, more than 130 European grants and 11 ERC grants, more than 350 patents or patent applications12 up start-ups and as many  which are about to be launched. The Institute’s scientific activity has been further strengthened since 2009 with the establishment of 11 research nodes throughout Italy (Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) and abroad (MIT and Harvard University, USA), which, along with the Genoa-based Central Lab, implement the research programs included in the 2015-2017 Strategic Plan.