I hold a Degree in Chemistry and a Ph.D. in Biochemistry. After my PostDoc period at the Center for Advanced Biotechnology at the University of Genova and at the National Cancer Institute, I joined IIT in 2010. Over my entire career, I focused my activity on bioanalytical chemistry and "omics" research, acquiring an extensive experience in the metabolomics, lipidomics and proteomics fields. I am currently PI in WP4, Core 3 of the EU Graphene Flagship Project Horizon 2020 (Grant agreement no. 696656), dedicated to the metabolomics and proteomics of graphene interactions with biological systems. I am also currently PI in project FFC#1-2021 from the Italian Cystic Fibrosis society, dedicated to the use of proteomics to identify new potential pharmacological targets. I am also the Coordinator of the Italian COVID-19 Mass Spec Coalition and President of the Italian Mass Spectrometry Society (IMaSS).
Andrea Armirotti
Analytical Chemistry Facility, Coordinator
Technologist - Facility CoordinatorAnalytical Chemistry
Telefono
+39 010 2896 938
Research center
CCT@Morego
Biografia
Education
Title: Degree in Chemistry
Institute: Università di Genova
Location: Genova
Country: Italy
From: 1996 To: null
Title: Ph.D. in Biochemistry
Institute: Università di Genova
Location: Genova
Country: Italy
From: 2003 To: null
Certificate
Title: Professional Certificate for Chemist
Description: null
Date: 15-12-2008
All Publications
2024
Setti A., Mariani D., Castagnetti F., Vitiello E., Stufera Mecarelli L., D'Angelo A., Santini T., di Timoteo G., Giuliani A., Perego E., Zappone S., Liessi N., Armirotti A., Vicidomini G., Bozzoni I.
ALS-associated FUS mutation reshapes the RNA and protein composition of Stress Granules
The RNA Society 29th Annual Meeting
Poster
Conference
2024
Silenzi V., D'Ambra E., Santini T., D'Uva S., Setti A., Salvi N., Nicoletti C., Scarfo R., Cordella F., Mongiardi B., Cavezza D., Liessi N., Ferrucci L., Ragozzino D., Armirotti A., Di Angelantonio S., De Leonibus E., Bozzoni I., Morlando M.
A tripartite circRNA/mRNA/miRNA interaction regulates glutamatergic signaling in the mouse brain
Cell Reports, vol. 43, (no. 10)
2024
Boselli L., Castagnola V., Armirotti A., Benfenati F., Pompa P.P.
Biomolecular Corona of Gold Nanoparticles: The Urgent Need for Strong Roots to Grow Strong Branches
Small, vol. 20, (no. 15)
2024
Montani C., Galbusera A., D'Epifanio B., Ghirardini E., Cornuti S., Pasquin Mariani J.R., De Guzman E., Mandrup Bertozzi S., Armirotti A., Baroncelli L., Gozzi A.
Connectomic and behavioral alterations in creatine transporter deficiency are partially normalized by gene therapy
bioRxiv
2024
Brindani N., Vuong L.M., La Serra M.A., Salvador N., Menichetti A., Acquistapace I.M., Ortega J.A., Veronesi M., Bertozzi S.M., Summa M., Girotto S., Bertorelli R., Armirotti A., Ganesan A.K., De Vivo M.
Discovery of CDC42 Inhibitors with a Favorable Pharmacokinetic Profile and Anticancer In Vivo Efficacy
Journal of Medicinal Chemistry, vol. 67, (no. 12), pp. 10401-10424
Scientific Talks
2023
Stuefer A., Balasco L., Gini S., Coletta L., Rocchi F., Montani C., Alvino F.G., Sastre D., Galbusera A., Aldrighetti M., Mandrup Bertozzi S., Lau Poui Cheung P., Vozzi D., Papaleo F., Iurilli G., Armirotti A., Cancedda L., Lombardo M., Bozzi Y., Gozzi A.
Transient neocortical excitatory / inhibitory imbalance during early infancy leads to permanent social impairments
SINS 2023
Conference
2022
Scarpelli R., Di Martino S., Tardia P., Cilibrasi V., Caputo S., Mazzonna M., Russo D., Penna I., Realini N., Margaroli N., Migliore M., Pizzirani D., Ottonello G., Mandrup Bertozzi S., Armirotti A., Nguyen D., Sun Y., Bongarzone E. R., Lansbury P., Liu M., Skerlj R.
Identification of ARN21641, an orally available and CNS penetrant Acid Ceramidase inhibitor with target engagement in mouse models of Gaucher and Krabbe diseases
27th National Meeting on Medicinal Chemistry (NMMC27) - Invited Talk
Conference
2022
Di Martino R.M.C., Russo D., Penna I., Tripathi S.K., Ottonello G., Bertozzi S.M., Girotto S., Armirotti A., Cruciani G., Bandiera T., Cavalli A., Bottegoni G.
Pursuing the complexity of bipolar disorder: rational design and optimization of first-in-class D3R/GSK-3β modulators towards an in vivo proof of concept
27th National Meeting on Medicinal Chemistry (NMMC27)
Conference
2020
Savardi A., Borgogno M., Narducci R., La Sala G., Ortega J.A., Summa M., Armirotti A., Bertorelli R., Contestabile A., De Vivo M., Cancedda L.
Discovery and Characterization of a Novel and Selective NKCC1 inhibitor to Rescue Cognitive Impairment in Down Syndrome
Sindrome di Down dalla Diagnosi alla Terapia
Conference
2019
Bramini M., Chiacchiaretta M., Rocchi A., Armirotti A., Cesca F., Benfenati F.
Graphene-based neural interfaces to target network excitability
FENS Regional Meeting 2019
Conference
Oral presentations
2018
Carli S., Trapella C., Armirotti A., Fantinati A., Ottonello G., Scarpellini A., Prato M., Fadiga L., Ricci D.
A new strategy to deliver Dexamethasone from PEDOT coatings
International Conference on Nanomedicine and Nanobiotechnology
Conference
2018
Carli S., Armirotti A., Trapella C., Prato M., Fadiga L., Biscarini F.
Conductive Polymers in Neuroscience: a Smart Drug Delivery Platform
Orbitaly Conference 2018
Conference