In 2015 the U-VIP (Unit for Visually Impaired People) research line, which to date is a cohesive and interdisciplinary team, started. The group's primary goal is to understand how our brain represents the environment to develop new solutions for sensory and motor-impaired children and adults. U-VIP Unit now consists of an interdisciplinary team including 20 scientists from different backgrounds: psychologists, physicists, and engineers. We are one of the few groups in Europe studying visual impairment and development from a scientific and technological point of view. At a methodological level, U-VIP uses a multidisciplinary methodology involving video and motion recording combined with psychophysical measurements to quantify typical and impaired individuals' perceptual and motor skills. We use Bayesian modelling to generate and validate predictions regarding multisensory skills and we use EEG and, more recently MRI to determine the neurofunctional architecture associated with impairment and rehabilitation. The main goal of the U-VIP unit is to study the neuroscientific mechanisms behind visual impairments in children and adults. Our ultimate goal is to support recovery by developing new devices and rehabilitation procedures. Identifying new rehabilitative solutions for early intervention is particularly urgent because, in 2019, there are still no technological solutions for young blind children. Our approach is based on the following milestones: firstly, we believe it is necessary to understand the mechanisms behind development to support the discovery of practical solutions. For this reason, we start with neuroscientific studies. Secondly, we develop new technological solutions grounded in scientific results and developed by strict collaboration with users and rehabilitators to reduce the impact of impairments in everyday life. Thirdly, we evaluate the efficacy of technology in clinical settings by performing rehabilitation training. Finally, we validate the technology scientifically by performing behavioral and neurophysiological studies to quantify its benefits. Although most of our efforts are focused on blindness, we have exploited this approach to study typical children (and development of education technology) and other disabilities (i.e., motor, audio, preterm and dyslexic children).