Dr. Silvia Giordani established the Nanocarbon Materials Lab (NACM) at the Istituto Italiano di Tecnologia in 2014. The unifying goal of the NACM lab is to develop a library of “smart” nanomaterials incorporating modular molecular components that can be interchanged and tailored for the precise development of nanosized sensors, imaging probes, delivery vehicles and diagnostic tools that can be used in a variety of biomedical applications and tailor-made technology platforms for targeted nanotherapeutics. The NACM research group is actively involved in the organic synthesis of molecular switches and the functionalisation of carbon nanomaterials. Research within the NACM Lab is aimed at the development of innovative materials for possible applications in biomedical research and technology. This experimental program therefore demands the design, the synthesis and the functionalization of carbon nanomaterials, requires expertise in synthetic organic chemistry, nanomaterial preparation and characterisation as well as in fluorescence imaging, microscopy and cancer biology. Additional research efforts are located in field of photo-responsive molecules and switchable materials.

  1. Theranostic Materials
    • Multi-functional carbon materials (carbon nano-onions, nanodiamonds, carbon nanotubes, graphene) for biomedical imaging, cancer diagnostics and therapy
  2. Switchable Materials
    • Spiropyran and azobenzene based photoswitches
    • Combination of switchable molecules with carbon nanomaterials

Laboratories

The laboratory is based in IIT in Genova. It’s a modern laboratory, in which the traditional organic synthesis is combined with innovative approaches. In addition we have access to a complete set of analytical techniques for the characterization of organic compounds and for the investigation of the physico-chemical properties of carbon nanomaterials. Access to bio lab allows us to test the synthesized nanomaterials for biocompatibility as well as their efficient cellular uptake.

Highlights

http://bcove.me/gtwyufp1 VIDEO ABSTRACT

http://www.radio24.ilsole24ore.com/player/riascolta/2016-01-07/smart-city/gSLAljSyUB RADIO24

http://www.etabeta.rai.it/dl/portaleRadio/media/ContentItem-ef4d2da3-6506-4d67-8242-99040e85f087.html  RAI

https://www.youtube.com/watch?v=wB9fBQ9CQgY ESOF 2012

Collaborations

  • Pier Paolo Pompa, IIT Lecce, EHS
  • Emilio Parisini, IIT@POLIMI, Milano
  • Francesco Nicassio, IIT@SEMM, Milano
  • Teresa Pellegrino, Genova, D3
  • Tiziano Bandiera, IIT Genova, D3
  • Raffaella Tonini, IIT Genova, NBT
  • Luca Berdondini, IIT Genova, NBT
  • Alberto Diaspro, IIT Genova, NAPH
  • Vittorio Pellegrini, IIT Genova, Graphene Labs

National

  • Prof. Claudia Tortiglione, CNR Pozzuoli «ecotoxicology of carbon nanomaterials
  • Dr. Giacomo Ceccone, JRC, Ispra «surface analysis of carbon nanomaterials

International

  • Prof. Eoin Scanlan, School of Chemistry, TCD “Synthesis of glycopeptides functionalized nano-onions”
  • Prof. Donal O’Shea, School of Chemistry, RCSI “NIR active nanomaterials”
  • Prof. Luis Echegoyen, Department of Chemistry, University of Texas El Paso, TX (USA) “Functionalization of fullerenes and carbon nano-onions”
  • Prof. Christer Aakeroy, Department of Chemistry, Kansas State University, Manhattan, KS (USA) “Supramolecular assembly and organization of responsive nanomaterials”