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Ferruccio Pisanello

Senior Researcher Tenured - Principal Investigator
Multifunctional Neural Interfaces with deep-brain regions
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About

Dr Pisanello is the coordinator of the Center for Biomolecular Nanotechnologies of the Italian Institute of Technology, where he is also head of the research unit “Multifunctional Neural Interfaces with deep brain regions”, established in June 2016 at the Center for Biomolecular Nanotechnologies of Fondazione Istituto Italiano di Tecnologia in Arnesano (Lecce, IT). Ferruccio Pisanello's research group strives at developing new paradigms to interface with the central nervous system, exploiting physical phenomena in unconventional ways to realize a new generation of devices able to gather multifunctional signals from the brain and to control its physiology.

Short Bio: Ferruccio Pisanello obtained the PhD degree in Physics at the University Pierre et Marie Curie in Paris in July 2011. He graduated summa cum laude (master degree) in telecommunication engineering at the University of Salento (Italy) in July 2008 with a thesis in photonic devices concerning the development of a biosensor based on photonic crystals. In January 2009 he obtained the pre-master degree of the Superior Institute for Interdisciplinary Instruction (ISUFI, Istituto Superiore Universitario Formazione Interdisciplinare). After his PhD in October 2011 he moved to Fondazione Istituto Italiano di Tecnologia (IIT), where he started to focus his research activity on new optoelectronic devices to study the central nervous system. In 2016 he received the ERC Starting Grant (“MODEM” Multipoint Optical DEvices for Minimally invasive neural circuits interface) for the development of a new class of optical and optoelectronic neural interfaces and started his independent group at the IIT. In 2018 he received from Elsevier the Micro and Nanoelectronic Engineering Young Investigator Award, given in Copenhagen during the 44th International Conference on Microelectronic Engineering. Since 2019 he is coordinator of the H2020 FET-OPEN project “NanoBright”, a European network aiming to exploit light-matter interactions to treat and control pathological states of the brain. Since 2021 his research group is partecipatiinng to the H2020 RIA project DEEPER and in the same year he has been awarded of the Proo-of-concept ERC Grant IN DEPTH. In 2024 he received the ERC Consolidator Grant (“MINING”) to generate novel computational methods and novel metal-dielectric materials to enhance nanoscale light-matter interaction to monitor brain activity.

At moment he is: author and coauthor of 77 Publications in International peer-reviewed Journals (including Science, Nature Methods, Nature Photonics, Nature Neuroscience, Nature Protocols, Neuron and Advanced Materials, list at https://orcid.org/0000-0002-1489-7758 ),holder of 5 High-Risk High-Gain competitive grants, author of 4 international patents (one patent pending). He is peer reviewer for major international journals (including Nature Electronics, Nature Communication and Advanced Materials), member of the editorial board of SPIE Neurophotonics, Scientific Reports and PLOS one, and he is serving as project reviewer for national research institutes in Netherland, Austria, Poland, France and Italy.

Top Publications
2024
Kazemzadeh M., Mehdipour I., De Vittorio M., Pisanello F.
An Autoencoder-Based Deep-Learning Method for Augmenting the Sensing Capability of Piezoelectric Microelectromechanical System Sensors in a Fluid-Dynamic System
Advanced Intelligent Systems, vol. 6, (no. 3)
Article Journal
2024
Pisano F., Masmudi-Martin M., Andriani M.S., Cid E., Kazemzadeh M., Pisanello M., Balena A., Collard L., Parras T.J., Bianco M., Baena P., Tantussi F., Grande M., Sileo L., Gentile F., De Angelis F., De Vittorio M., Menendez de la Prida L., Valiente M., Pisanello F.
Vibrational fiber photometry: label-free and reporter-free minimally invasive Raman spectroscopy deep in the mouse brain
Nature Methods
2023
de Marzo G., Mastronardi V.M., Algieri L., Vergari F., Pisano F., Fachechi L., Marras S., Natta L., Spagnolo B., Brunetti V., Rizzi F., Pisanello F., De Vittorio M.
Sustainable, Flexible, and Biocompatible Enhanced Piezoelectric Chitosan Thin Film for Compliant Piezosensors for Human Health
Advanced Electronic Materials, vol. 9, (no. 9)
2022
Spagnolo B., Balena A., Peixoto R.T., Pisanello M., Sileo L., Bianco M., Rizzo A., Pisano F., Qualtieri A., Lofrumento D.D., De Nuccio F., Assad J.A., Sabatini B.L., De Vittorio M., Pisanello F.
Tapered fibertrodes for optoelectrical neural interfacing in small brain volumes with reduced artefacts
Nature Materials, vol. 21, (no. 7), pp. 826-835
2021
Montinaro C., Pisanello M., Spagnolo B., Bianco M., Pisano F., Balena A., De Nuccio F., Lofrumento D.D., Verri T., De Vittorio M., Pisanello F.
Influence of anatomical features of different brain regions on the spatial localization of fiber photometry signals
Biomedical Optics Express
Article in Press Journal
Awards and Achievements
2024
Collard L., Kazemzadeh M., Piscopo L., De Vittorio M., Pisanello F.
EDITORS' PICK for "Exploiting holographically encoded variance to transmit labelled images through a multimode optical fiber"
2024
Kazemzadeh M., Collard L., Pisano F., Piscopo L., Ciraci C., Vittorio M.D., Pisanello F.
Editors' pick for "Unwrapping non-locality in the image transmission through turbid media"
2023
Zheng D., Pisano F., Collard L., Balena A., Pisanello M., Spagnolo B., Mach-Battle R., Tantussi F., Carbone L., De Angelis F., Valiente M., Liset D.L.P., Ciracì C., De Vittorio M., Pisanello F.
SELECTED FOR FRONTISPICE on ADVANCED MATERIALS "Toward Plasmonic Neural Probes: SERS Detection of Neurotransmitters through Gold-Nanoislands-Decorated Tapered Optical Fibers with Sub-10 nm Gaps"
2023
Pisano F., Kashif M.F., Balena A., Pisanello M., De Angelis F., de la Prida L.M., Valiente M., D'Orazio A., De Vittorio M., Grande M., Pisanello F.
TOP DOWNLOAD FOR "Plasmonics on a Neural Implant: Engineering Light-Matter Interactions on the Nonplanar Surface of Tapered Optical Fibers"
2022
Montinaro C., Pisanello M., Bianco M., Spagnolo B., Pisano F., Balena A., De Nuccio F., Lofrumento D. D., Verri T., De Vittorio M., Pisanello F.
Endoscopy and Fiber Optics: Top Downloads from Biomedical Optics Express
Editorships
2021
Pisanello F.
Frontiers in Neuroscience
2021
Pisanello F.
Neurophotonics
Organized Events
2024
Pisanello F., Ciracì C., De Vittorio M.
4th and final review meeting EIC project NANOBRIGHT
2023
Pisanello F., Ciracì C., De Angelis F., De Vittorio M.
3rd review meeting EIC project NANOBRIGHT
2023
De Vittorio M., Fellin T., Pisanello F., Pisano F.
8th International Workshop on Technologies for Optogenetics and Neurophotonics - OPTOGEN2023
2023
Pisanello F., Fellin T., De Vittorio M.
8th International Workshop on Technologies for Optogenetics and Neurophotonics - OPTOGEN2023
2022
Collard L., Pisano F., Ciraci C., De Angelis F., De Vittorio M., Pisanello F.
Nanobright summary