The goal of the Asymmetric Catalysis and Photochemistry Research Line is to develop new general catalysis concepts and applying them to the synthesis of complex molecules and pharmaceuticals. Our approach is based on the combination of two powerful fields of molecule activation: visible light photocatalysis and metal-free organocatalysis. The motivation is that the use of light excitation, to bring a molecule from its ground state to an electronically excited state, can unlock previously inaccessible reaction pathways, thereby creating new synthetic opportunities.
We aim to develop fundamentally new and ground-breaking strategies to asymmetric catalysis via the intermediacy of light-mediated redox processes and excited-state reactivity patterns.
The main interest is on the discovery and mechanistic elucidation of new enantioselective organocatalytic and photochemical processes that address unsolved problems in synthetic methodology. Our research on light-driven stereocontrolled reactions aims at increasing process efficiency using a mechanistically-guided approach, controlling reaction selectivity, and reducing the environmental impact of chemical synthesis.
ERC Consolidator Grant, grant agreement no. 681840
CATA-LUX - Light-Driven Asymmetric Organocatalysis
Funding agency: ERC (European Research Council
Period: from 1-Nov-2016 till 30-Oct-2021